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Circular Dichroism Spectrometer J-1000 Series

The latest achievement in the JASCO commitment to lead the field of Circular Dichroism

JASCO J-1000 … Opens the Door to the Future of Circular Dichroism

Chiroptical spectroscopy has become one of most important techniques for the characterization of biomolecules, determination of absolute configuration and stereochemical analysis. Based on JASCO's experience in CD instrumentation over a half century, JASCO proudly introduces the J-1000 Series Circular Dichroism (CD) Spectrometers providing both unparalleled optical performance and versatile flexibility.

The latest Quad Lock-in Amplifier allows the simultaneous acquisition of up to four data channels including CD, Absorbance, Linear Dichroism (LD), Fluorescence, Fluorescence detected CD (FDCD), Fluorescence detected LD (FDLD), Fluorescence Anisotropy and Optional Rotatory Dispersion (ORD).

Designed as a “Chiroptical Spectroscopy Workbench” the J-1500 offers a wide range of accessories to allow it to be adapted to any application requirements. Temperature ramping, protein folding, enzyme kinetics, DNA/RNA interactions, natural organic chemistry, biochemistry, macromolecules and rapid scanning experiments are all possible.

KEY FEATURES

  • Wide spectral range from vacuum UV to Near-IR (up to 1600 nm, only J-1500)
  • Standard built-in mercury lamp and optional NIST traceable standard sample for system validation
  • High-efficiency purge capability enabling to enhanced vacuum UV measurement
  • Extremely low stray light and high S/N ratio providing wide dynamic range
  • High speed scanning (J-1500: 10000 nm/min, J-1100: 5000 nm/min)
  • Simultaneous Multi-probe measurements (SMP) with acquisition of up to four data channels
  • Flexible design allowing field upgrades for different measurement modes and accessories as applications evolve
  • Spectra Manager II or Spectra Manager CFR (For FDA regulated labs): 64 bit innovative, cross-platform Spectroscopy
  • Software Suite for data acquisition, analysis and presentation including several methods of secondary structure calculation
     

Unique Optical Features and Benefits

  • Compact benchtop design
  • Air cooled 150W Xenon lamp
  • Highest Signal-to-Noise ratio
  • Range of precise temperature control accessories
  • Automated titration and stopped-flow accessories
  • Spectra Manager™ II software for control and data analysis
  • Spectra Manager™ CFR option for 21 CFR 11 compliance
  • Flexible design allows field upgrades for different measurement capabilities
  • Upgrade accessories as applications and budgets evolve

Versatility for a wide range of application requirements

  • Protein folding studies
  • Protein conformational studies
  • DNA/RNA interactions
  • Enzyme kinetics
  • Purity testing of optically active substances
  • Quantitative analysis of pharmaceuticals
  • Natural products chemistry
  • Biochemistry and macromolecules
  • Rapid scanning (time resolved) experiments

JASCO offers a range of measurement modes and hyphenated techniques

  • Circular Dichroism (CD) and UV-Vis Absorbance (standard)
  • Scanning Emission Fluorescence and Fluorescence detected CD (FDCD)
  • Automated titration and thermal ramping
  • Linear dichroism (LD), Optical Rotatory Dispersion (ORD, and Diffuse Reflectance/Transmittance CD (DRCD/DTCD)
  • Stopped-flow CD, Stopped-flow absorbance, Stopped-flow fluorescence
  • High throughput CD (HTCD)
  • Magnetic CD (MCD)
  • Chiral HPLC detection (LCCD)
  • Near infrared CD

 

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